RHEOLOGICAL PROPERTIES OF BLOOD AT BASAL CELL SKIN
CANCER IN THE NEAREST POSTOPERATIVE PERIOD

Maslyakov Vladimir Vladimirovich, Doctor of medical sciences, professor, vice-rector for research and public relations, head of sub-department of clinical medicine, “Reavis” Medical University (building 10, Verhny rynok street, Saratov, Russia), maslyakov@inbox.ru
Vlasenko Yuliya Borisovna, Postgraduate student, “Reavis” Medical University (building 10, Verhny rynok street, Saratov, Russia), saratov@reaviz.ru
Kim Larisa Mikhaylovna, Postgraduate student, “Reavis” Medical University (building 10, Verhny rynok street, Saratov, Russia), saratov@reaviz.ru

616.5-006.61-097

10.21685/2072-3032-2016-3-6

Background. For the purpose of studying the changes of the cellular link of the immune status and rheological properties of blood in patients with basal cell skin cancer in the course of surgical treatment the authors examined 39 patients at the age of 65 ± 3 years old. The research was conducted before surgical treatment, during the first postoperative days, on the fifth, seventh, tenth postoperative day.
Materials and methods. Rheological properties of blood were examined among 39 patients, the age of patients was 65 ± 3 years old. The research was conducted before surgical treatment, during the first postoperative days, on the fifth, seventh, tenth postoperative day. For comparison the authors studied indicators of rheologi-cal properties of blood of 17 relatively healthy volunteers of the same age and sex (group of comparison 1) and 20 patients subject to skin fibroma surgery (group of comparison 2), the age and sex of patients from group of comparison 2 were similar to those of the main group, the indicators were examined on the same days. The di-agnosis of all the patients was confirmed morphologically before surgical treatment. The viscosity of blood was examined by means of a rotational AKP-2 viscometer at shear rates: 200; 100; 150; 50 and 20 sec–1.
Results. It has been established that patients with basal cell cancer have in-creased indicators of rheological properties of blood prior to surgical treatment at all shear rates, the index of aggregation of erythrocytes, the index of deformability of erythrocytes, hematocrit and the degree of efficiency of oxygen delivery to tissues. During the first postoperative days one may observe a substantial increase of rheological properties of blood at all shear rates. Surgical treatment of basal cell skin cancer leads only to partial restoration of indicators of viscosity of blood at high shear rates.

basal cell skin cancer, rheological properties of blood.

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